Saturday 23 March 2013

The Role of Serotonin in Alcohol’s Effects on the Brain http://www.currentseparations.com/issues/18-1/cs18-1d.pdf

http://www.currentseparations.com/issues/18-1/cs18-1d.pdf

Serotonin is an important brain chemical that acts as a neurotransmitter

to communicate information among nerve cells. Serotonin’s actions have

been linked to alcohol’s effects on the brain and to alcohol abuse.

Alcoholics and experimental animals that consume large quantities of

alcohol show evidence of differences in brain serotonin levels compared

with nonalcoholics. Both short- and long-term alcohol exposures also

affect the serotonin receptors that convert the chemical signal produced

by serotonin into functional changes in the signal-receiving cell.

Drugs that act on these receptors alter alcohol consumption in both

humans and animals. Serotonin, along with other neurotransmitters,

also may contribute to alcohol’s intoxicating and rewarding effects,

and abnormalities in the brain’s serotonin system appear to play an

important role in the brain processes underlying alcohol abuse.

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